Faculty

Novel techniques for correcting type-1 diabetes without insulin, utilizing the beneficial effects of healthy adipose tissue: Subcutaneous transplantation of embryonic brown adipose tissue (BAT) has proven effective in reversing type 1 diabetes in mice, independent of insulin.

The He Lab is dedicated to advancing knowledge of the mechanisms responsible for colorectal tumor progression, with a specific focus on Stress and its influence on the Tumor Microenvironment.

The Huettner lab uses electrophysiology to study native and recombinant mammalian glutamate receptors, in order to elucidate their interactions with components of the lipid bilayer, and their pharmacology and role in synaptic transmission.

The Jansen Lab is focused on elucidating the molecular mechanisms that regulate the architecture, dimensions and dynamics of actin filament networks, and tune them to support essential cellular functions ranging from cell migration and cytokinesis to neurogenesis.

The Kast Lab studies the biogenesis and dynamics of intracellular membrane compartments; molecular mechanisms and regulation of cytoskeleton and membrane interactions.

The Klyachko Lab studies the mechanisms governing synaptic transmission are critical to our understanding of how information is transmitted in the brain, yet they remain among the most fundamental unresolved questions in neurobiology.

Molecular basis of ion channel function, and in particular on membrane lipid-channel interactions.

The Lishko Lab focuses on molecular mechanisms of bioactive lipid signaling, investigating bioelectricity and regulation of ion channels, physiology of the retina, fluid flow in the brain, fertility, reproductive biology research, neurodegeneration and vision.

The Major Lab uses mass spectrometry-based proteomics and chemical and genetic screens to study signal transduction in human disease, with a particular focus on understudied kinases and the WNT and the KEAP1/NRF2 pathways.

Structure, function and regulation of mechanosensitive ion channels.