Pyrimethamine and a potent analog inhibit NRF2 by suppressing one-carbon metabolism

Chembo J, Bowman BM, Lapak K, Wilkerson E, Wamsley NT, Paiboonrungruang C, Cho K, Medcalf MR, Wang H, Patti GJ, Dolle RE, Chen X, Zolkind P, Major MB

Chembo J, Bowman BM, Lapak K, Wilkerson E, Wamsley NT, Paiboonrungruang C, Cho K, Medcalf MR, Wang H, Patti GJ, Dolle RE, Chen X, Zolkind P, Major MB