Klyachko Lab

Synaptic Transmission | Neurotransmitter Release | Fragile X Syndrome | FMRP | Autism | GABAergic Inhibition | Neural Circuits | Super Resolution Microscopy | Electrophysiology | Modeling

The goal of our research program is to develop and apply nanoscale resolution approaches to understand the fundamental mechanisms of synaptic transmission in central synapses under normal conditions, and how disruptions in synaptic functions lead to disease states, particularly Fragile X syndrome and Alzheimer’s disease.