Klyachko Lab
McDonnell Sciences Building (MS: 8228-0012-05)
314-362-5518
klyachko@wustl.edu
Synaptic Transmission | Neurotransmitter Release | Fragile X Syndrome | FMRP | Autism | GABAergic Inhibition | Neural Circuits | Super Resolution Microscopy | Electrophysiology | Modeling
The goal of our research program is to develop and apply nanoscale resolution approaches to understand the fundamental mechanisms of synaptic transmission in central synapses under normal conditions, and how disruptions in synaptic functions lead to disease states, particularly Fragile X syndrome and Alzheimer’s disease.