Ashrafi Lab

McDonnell Sciences Building (MS: 8228-0012-05)

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Neurotransmission | Neurometabolism | Glycolysis | Mitochondrial Function | Synaptic Imaging | Neurodegeneration | Epilepsy

The overarching goal of the Ashrafi lab is to interrogate the metabolic regulation of synaptic transmission. We combine state-of-the-art imaging of single synapses with proteomic and genomic analysis to determine how metabolic pathways are regulated in the nervous system. We also investigate the dysregulation of mitochondrial and glycolytic energy metabolism in a variety of neurological disorders such as Parkinson’s disease and epilepsy