Erath J, and Djuranovic S
Protein proximity networks and functional evaluation of the Casein Kinase 1 γ family reveals unique roles for CK1γ3 in WNT signaling (Links to an external site)
Agajanian MJ, Potjewyd FM, Bowman BM, Solomon S, LaPak KM, Bhatt DP, Smith JL, Goldfarb D, Axtman AD, and Major MB
Pagliarini named Hugo F. and Ina C. Urbauer Professor (Links to an external site)
Recognized for work on mitochondria, powerhouses of the cell.
Protein linked to intellectual disability has complex role (Links to an external site)
Finding therapies for fragile X may depend on understanding the many ways protein’s loss affects brain.
BIO Doubles Insulin Output Over Legacy Manufacturing Methods, Putting Company on Track to Reduce Insulin Costs by 30% (Links to an external site)
Just one year after successfully demonstrating lab-scale production of human insulin using synthetic biology techniques, rBIO recently concluded a successful optimization project with WashU, and firms its path toward commercialization and large-scale production.
A short translational ramp determines the efficiency of protein synthesis￼ (Links to an external site)
Verma M, Choi J, Cottrell KA, Lavagnino Z, Thomas EN, Pavlovic-Djuranovic S, Szczesny P, Piston DW, Zaher HS, PuglisiJD, and Djuranovic S
LTBP1 promotes fibrillin incorporation into the extracellular matrix (Links to an external site)
Przyklenk M, Georgieva VS, Metzen F, Mostert S, Kobbe B, Callewaert B, Sengle G, Brachvogel B, Mecham RP, Paulsson M, Wagener R, Koch M, and Schiavinato A
Visualizing an allosteric intermediate using CuAAC stabilization of an NMR mixed labeled dimer (Links to an external site)
Sapienza P, Currie M, Lancaster N, Li K, Aubé J, Goldfarb D, Cloer E, Major MB, Lee A ACS Chemical Biology, 2021
Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract (Links to an external site)
Zhang J, Morgan EW, Sanidad KZ, Zhang H, Liang Y, Zhao E, Chacon-Vargas K, Yeliseyev V, Parsonnet J, Haggerty TD, Wang G, Simpson JB, Jariwala PB, Beaty VV, Yang J, Yang H, Panigrahy A, Minter LM, Kim D, Gibbons JG, Liu L, Li Z, Xiao H, Borlandelli V, Overkleeft HS, Cloer EW, Major MB, Goldfarb D, Cai Z, Redinbo MR, Zhang G Nature Communications, 2022
High-throughput methodology to identify CRISPR-generated Danio rerio mutants using fragment analysis with unmodified PCR products (Links to an external site)
Colijn S, Yin Y, and Stratman AN