1980s
Receptor-mediated Endocytosis of Transferrin and of the Transferrin Receptor in Rat Reticulocytes Recycling

Receptor-mediated Endocytosis of Transferrin and of the Transferrin Receptor in Rat Reticulocytes Recycling (Links to an external site)

At 4°C transferrin bound to receptors on the reticulocyte plasma membrane, and at 37°C receptor-mediated endocytosis of transferrin occurred. Uptake at 37°C exceeded binding at 4°C by 2.5-fold and saturated after 20-30 min. During uptake at 37°C, bound transferrin was internalized into a trypsin-resistant space. Read Full Publication (PDF)

1920s
A Study of the Action Currents of Nerve With the Cathode Ray Oscillograph

A Study of the Action Currents of Nerve With the Cathode Ray Oscillograph (Links to an external site)

The instruments which have been used heretofore for the observation of nerve action currents have been galvanometers of the moving coil or magnet type with or without the aid of a rheotome, the capillary electrometer and the string galvanometer. Each of these instruments possesses considerable inertia. The slower galvanometers are unaffected by single action currents and give a sustained deflection when the action currents are monophasic and rapidly repeated. Read Full Publication (PDF)