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Ghazaleh Ashrafi, PhD

Ghazaleh Ashrafi, PhD

Assistant Professor of Cell Biology & Physiology

The Ashrafi lab uses genetic, biochemical, and quantitative optical imaging techniques to study metabolic regulation of neurotransmission.

Kendall Blumer, PhD

Kendall Blumer, PhD

Professor of Cell Biology & Physiology

The Blumer lab currently studies signal transduction mechanisms that cause uveal melanoma, a highly aggressive and deadly cancer, with the ultimate goal of discovering avenues leading to effective therapy for this currently untreatable cancer.

Chun-Kan Chen, PhD

Chun-Kan Chen, PhD

Assistant Professor of Cell Biology & Physiology

The Chen lab utilizes multi-omic and high-throughput screening approaches to systematically investigate the regulation and function of circRNA in cells and develop novel circRNA technologies for translational applications.

Clair  Crewe, PhD

Clair Crewe, PhD

Assistant Professor of Cell Biology & Physiology

The Crewe lab uses transgenic mouse lines, cell culture and biochemistry to understand extracellular vesicle (EV)-mediated signaling during homeostatic and pathologic metabolic regulation.

Pan-Yue  Deng, MD, PhD

Pan-Yue Deng, MD, PhD

Associate Professor of Cell Biology & Physiology

Lai Kuan Dionne, PhD

Lai Kuan Dionne, PhD

Assistant Professor of Cell Biology & Physiology

Inter-organellar interactions between midbody, centrosome, and primary cilium in health and disease.

Sergej Djuranovic, PhD

Sergej Djuranovic, PhD

Professor of Cell Biology & Physiology

The Djuranovic Lab uses different biochemical, molecular biology and genetics techniques to investigate the process of gene expression regulation at the level of mRNA translation.

Dennis Goldfarb, PhD

Dennis Goldfarb, PhD

Assistant Professor of Cell Biology & Physiology

The Goldfarb Lab is focused on computational mass spectrometry and proteomics with the goal of achieving comprehensive protein identification and quantification in complex biological samples.

Subhadra Gunawardana,  DVM, PhD

Subhadra Gunawardana, DVM, PhD

Associate Professor of Cell Biology and Physiology

Novel techniques for correcting type-1 diabetes without insulin, utilizing the beneficial effects of healthy adipose tissue: Subcutaneous transplantation of embryonic brown adipose tissue (BAT) has proven effective in reversing type 1 diabetes in mice, independent of insulin.

Xue-Yan He, PhD

Xue-Yan He, PhD

Assistant Professor of Cell Biology & Physiology

The He Lab is dedicated to advancing knowledge of the mechanisms responsible for colorectal tumor progression, with a specific focus on Stress and its influence on the Tumor Microenvironment.

James E. Huettner, PhD

James E. Huettner, PhD

Professor of Cell Biology & Physiology

The Huettner lab uses electrophysiology to study native and recombinant mammalian glutamate receptors, in order to elucidate their interactions with components of the lipid bilayer, and their pharmacology and role in synaptic transmission.

Silvia Jansen, PhD

Silvia Jansen, PhD

Assistant Professor of Cell Biology & Physiology

The Jansen Lab is focused on elucidating the molecular mechanisms that regulate the architecture, dimensions and dynamics of actin filament networks, and tune them to support essential cellular functions ranging from cell migration and cytokinesis to neurogenesis.

David J. Kast, PhD

David J. Kast, PhD

Assistant Professor of Cell Biology & Physiology

The Kast Lab studies the biogenesis and dynamics of intracellular membrane compartments; molecular mechanisms and regulation of cytoskeleton and membrane interactions.

Vitaly A. Klyachko, PhD

Vitaly A. Klyachko, PhD

Professor of Cell Biology & Physiology

The Klyachko Lab studies the mechanisms governing synaptic transmission are critical to our understanding of how information is transmitted in the brain, yet they remain among the most fundamental unresolved questions in neurobiology.

Sun Joo Lee, PhD

Sun Joo Lee, PhD

Assistant Professor of Cell Biology & Physiology

Molecular basis of ion channel function, and in particular on membrane lipid-channel interactions.

Polina Lishko, PhD

Polina Lishko, PhD

Professor of Cell Biology & Physiology
BJC Investigator

The Lishko Lab focuses on molecular mechanisms of bioactive lipid signaling, investigating bioelectricity and regulation of ion channels, physiology of the retina, fluid flow in the brain, fertility, reproductive biology research, neurodegeneration and vision.

M. Benjamin Major, PhD

M. Benjamin Major, PhD

Alan A. and Edith L. Wolff Professor
Department of Cell Biology & Physiology
Department of Otolaryngology

The Major Lab uses mass spectrometry-based proteomics and chemical and genetic screens to study signal transduction in human disease, with a particular focus on understudied kinases and the WNT and the KEAP1/NRF2 pathways.

Grigory I. Maksaev, PhD

Grigory I. Maksaev, PhD

Instructor in Cell Biology & Physiology

Structure, function and regulation of mechanosensitive ion channels.

Dario  Maschi, PhD

Dario Maschi, PhD

Assistant Professor of Cell Biology & Physiology

Developing new approaches for studying synaptic function using super-resolution live imaging microscopy and advanced computational imaging analysis

Jongyun Myeong, PhD

Jongyun Myeong, PhD

Instructor in Cell Biology & Physiology

Colin G. Nichols, PhD

Colin G. Nichols, PhD

Carl Cori Professor, Department of Cell Biology & Physiology
Director, Center for the Investigation of Membrane Excitability Diseases

The Nichols Lab’s research spans from the molecular basis of potassium channel activity to human disease. His work on KATP channel activity led to the discovery of the mechanism of human neonatal diabetes and a revolution in therapy – affected children can now take once a day pills – even dissolved in milk – rather than traumatic, three times a day insulin injections.

David J. Pagliarini, PhD

David J. Pagliarini, PhD

Hugo F. & Ina C. Urbauer Professor and BJC Investigator
Departments of Cell Biology & Physiology, Biochemistry and Molecular Biophysics, and Genetics

The Pagliarini Lab is an interdisciplinary team of scientists driven to understand the biochemical underpinnings of mitochondrial dysfunction in human diseases.

Slavica  Pavlovic-Djuranovic, PhD

Slavica Pavlovic-Djuranovic, PhD

Assistant Professor of Cell Biology & Physiology

David W. Piston, PhD

David W. Piston, PhD

Edward J. Mallinckrodt, Jr. Professor and Head of Cell Biology & Physiology

The Piston Lab studies the molecular pathways of islet hormone secretion.

Paul H. Schlesinger, MD, PhD

Paul H. Schlesinger, MD, PhD

Associate Professor of Cell Biology & Physiology

Study several areas that focus on cell membrane function, including activation, and in-membrane dynamics of BCl-2 family proteins, the critical arbiters of cell death in humans, pore forming antimicrobial peptides, membrane repair, perflurocarbon nano-delivery systems, malaria parasite host/cell interactions.

Sheila A. Stewart, PhD

Sheila A. Stewart, PhD

Gerty Cori Professor and Vice Chair, Department of Cell Biology & Physiology
Professor, Department of Medicine

The Stewart lab’s research focuses on understanding how age-related changes in noncancerous cells (referred to as stroma) participate in cancer development.

Amber Stratman, PhD

Amber Stratman, PhD

Assistant Professor of Cell Biology & Physiology

The Stratman Lab studies the mechanisms regulating blood vessel formation, stabilization, and blood flow sensing during development and disease.

Heather L. True, PhD

Heather L. True, PhD

David English Smith Professor, Department of Cell Biology & Physiology

The True Lab studies protein misfolding and aggregation are the hallmark of several neurodegenerative diseases and other disorders.

Nathaniel York, PhD

Nathaniel York, PhD

Instructor in Cell Biology & Physiology

Impact of gain- and loss-of-function in KATP on smooth muscle cell electrophysiology.

Zhongsheng You, PhD

Zhongsheng You, PhD

Professor of Cell Biology & Physiology

The You Lab studies the DNA damage response and replication stress response in human cells that are essential for genome maintenance and cancer avoidance.

Emily W. Zarbock, PhD

Emily W. Zarbock, PhD

Instructor in Cell Biology & Physiology

Mass Spectrometry, Proteomics